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Premature rupture of membranes (PPROM) can occur in up to 3–4.5% of pregnancies and lead to complications in the mother and fetus. Maternal chorioamnionitis is the most common complication and may even lead to sepsis. In the fetus, depending upon the time of PPROM causing oligohydramnios, the effect on the lung growth is variable leading to varying degrees of pulmonary hypoplasia with its associated complications like persistent pulmonary hypertension of the newborn (PPHN), air leaks and respiratory failure. Here we present a successful outcome following PPROM at about 18 weeks of gestation, with severe oligohydramnios leading to preterm delivery with suspected pulmonary hypoplasia and pneumothorax in the baby.

case reports in perinatal medicine

Successful outcome of a preterm infant with severe oligohydramnios and suspected pulmonary hypoplasia following premature rupture of membranes (PPROM) at 18 weeks’ gestation