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Severe major limb abnormalities of the fetus found by antenatal ultrasound screening are often difficult to be accepted by pregnant women. We experienced two cases with fibular aplasia, tibial campomelia, and oligosyndactyly (FATCO) syndrome, and Cornelia de Lange syndrome (CdLS). Appropriate perinatal care coordinated by obstetricians, pediatric specialists, genetic counselors, nurses, and social workers successfully ensured the better acceptance of the parents toward the severe anomalies complicated in the newborn. In this report, we described the two cases of patients with fetuses prenatally diagnosed with severe fetal limb anomalies.

Importance of perinatal care for pregnant women with severe fetal multiple limb abnormalities