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CHEMISTRY International September-October 2012 what happens when you downscale it.” He described the change in properties from bulk, to thin coating to nanoscale as discontinuous. “There is a lot for us to do in this nanospace to develop new materials.” The final question of the event went to Steven Freeman, who teaches innovation at the University of Pennsylvania. He asked for an example of radical change versus the incremental changes described in much of the discussion. Connelly answered first. “I think there is a basic change in the way biology is going to impact the materials sciences. We engineer biological process and produce very specific products at room temperature, atmospheric pressure and in aqueous media with no exotic metals.” Pappas said the incremental advances in materials over the past 20 to 30 years add up a major change. “Breakthroughs are the sum of incremental changes over time,” he said.

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