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Following the 100 Year Anniversary of IUPAC celebrated in Paris in 2019, Artificial Intelligence was made the focus of the following global 2021 World Chemistry Leadership Meeting (WCLM).  Note: The program of WCLM 2021 is available online. A detailed account of WCLM2021 will follow in the next issue of Chem Int. at  https://iupac.org/event/wclm2021/ .   Once it was clear the prevailing COVID-19 conditions would mean that the 2021 WCLM would be virtual, the planning committee decided to take advantage of an online setting to have a truly global meeting and to have the event follow the sun round the world using three time zones and “visiting” the next two IUPAC Congress sites,  i.e.  The Netherlands 2023 and Malaysia 2025.

Artificial Intelligence and Chemistry: How do we shape the future? What are the critical issues to be addressed by IUPAC?