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Dodecanoyl isothiocyanate ( I ) reacts additively with anthranilic acid to afford derivatives of thiourea  II  and benzothiazine  III  in a one-pot reaction. The cyclisation of thiourea  II  was achieved using acetic anhydride to form quinazoline derivative  IV . The heating of quinazoline  IV  in acetic anhydride or butan-1-ol gave quinazoline derivatives  V  or  VI , respectively. Benzothiazine  III  underwent trans-acylation to benzothiazine  VII  in boiling acetic anhydride. The treatment of  IV  with hydrazine hydrate, anthranilic acid or ethyl carbazate afforded derivatives of triazoloquinazoline  VIII , quinazolinoquinazoline  XI  or thiosemicarbazide  X , respectively. The reaction of  I  with 2aminophenol or 2-aminothiophenol afforded thiourea derivative  XIII  or benzothiazole derivative  XIV , respectively. Most of the synthesised compounds bear a lauroyl (dodecanoyl) group (a hydrocarbon moiety). The structures of the synthesised compounds were confirmed by microanalytical and spectral data.

Use of dodecanoyl isothiocyanate as building block in synthesis of target benzothiazine, quinazoline, benzothiazole and thiourea derivatives