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The titled compound 1,4-diazacycloheptane have vibrational freedom which allows it to coordinate to metal through 1 st  and 4 th  positions. Copper (II) and Nickel (II) complexes of DACH were prepared and characterized through UV-Visible, FT-IR, elemental analyses, conductance, and magnetic susceptibilities and compared to the results published in  Inorg. Chem ., 8(3), 528 (1969). The prepared complexes bearing different coordinating or non-coordinating anions were screened against four different pathogenic bacterial strains to study anionic effect on antibacterial activity. The MIC values of all the compounds suggest that [Cu(DACH) 2 Br 2 ] is almost inactive against the tested microbes except  Staph aureus . Rest of the metal complexes are active at their respective MIC values.

Antibacterial Activities of Transition Metal complexes of Mesocyclic Amidine 1,4-diazacycloheptane (DACH)