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A key component of an intensity-based 2D/3D registration is the digitally reconstructed radiograph (DRR) module, which creates 2D projections from pre-operative 3D data, e.g., CT and MRI scans. On average, an intensity-based 2D/3D registration requires ten iterations and the rendering of twelve DRR images per iteration. In a typical DRR implementation, the rendering time is about two seconds, and the registration runtime is four minutes. We present an implementation of the Siddon-Jacobs algorithm that uses a novel pixel-step approach to determine the pixel location of the rendering plane. In addition, we calculate the intensity of each pixel in the rendering plane using a parallel computing approach. The DRR rendering time is reduced to 10ms on average so that the registration runtime can be achieved in an average of 4.8 seconds.

current directions in biomedical engineering

An Ultra-Fast Digitally Reconstructed Radiograph (DRR) Implementation of the Siddon-Jacobs Algorithm using Parallel Computing: Runtime Improvement of an Intensity-Based 2D/3D Registration