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Background:  The Luminescent Oxygen Channeling Immunoassay (LOCI ® ) technology is a well-established homogeneous assay format that allows for fast, accurate, and highly sensitive quantitation of analytes. We set out to develop and prove a novel concept to establish a LOCI format that should principally allow for the determination of the activity of coagulation factors and anticoagulants of clinical relevance.

Coagulation assays based on the Luminescent Oxygen Channeling Immunoassay technology 1)