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Background:  A recent genome-wide linkage study mapped blood pressure (BP)-related loci on human chromosome 1q and identified the regulator of G-protein signaling 5 ( RGS5 ) as a candidate for regulation of BP. Thus, we assessed the relationship between  RGS5  genetic polymorphisms and essential hypertension (EH) in Chinese.

Haplotype-based association of regulator of G-protein signaling 5 gene polymorphisms with essential hypertension and metabolic parameters in Chinese