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Background:  The β1-adrenergic receptor (ADRB1) plays a pivotal role in mediating signal transduction of the sympathetic-adrenal system, which is involved in the regulation of cardiac output and peripheral resistance. Our goal was to determine whether the polymorphisms Arg389Gly (rs1801253) and Ser49Gly (rs1801252) of the  ADRB1  gene were associated with essential hypertension in Chinese.

Polymorphisms of the β1-adrenergic receptor gene are associated with essential hypertension in Chinese