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Background:  We recently hypothesized that serum γ-glutamyltransferase (GGT), within its reference range, predicts many diseases as a biomarker for background exposure to various xenobiotics. Even though normal serum GGT was associated with xenobiotics having very long half-lives (heavy metals, dioxin, or organochlorine pesticides), it was unknown whether GGT was associated with xenobiotics with short half-lives, including polycyclic aromatic hydrocarbons (PAHs), well known carcinogens.

Is serum γ-glutamyltransferase an exposure marker of xenobiotics? Empirical evidence with polycylic aromatic hydrocarbon