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Background:  Serum β 2 -microglobulin (β2m) has been established as a marker of disease activity in malignancies, autoimmune conditions and infections. Despite its important role in prognosis assessment and disease monitoring, relatively few studies are available on its expression in healthy individuals. Furthermore, interpretation of results is hampered by the variety in reference limits due to differences in methodology, sample population and statistics.

Serum β 2 -microglobulin measured by immunonephelometry: expression patterns and reference intervals in healthy adults