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Background : Recently, the role of the  FTO  (fat mass and obesity associated) gene in obesity development was described in Western European, but not in Oceanic, cohorts. The objective of this study was to test the hypothesis that the  FTO  single nucleotide polymorphism (SNP) is associated with body mass index (BMI) in the Slavic population and to analyze if there could be sex-specific effects of the SNP on BMI, waist-to-hip ratio (WHR), and lipid parameters.

clinical chemistry and laboratory medicine

A common variant in the  FTO  gene is associated with body mass index in males and postmenopausal females but not in premenopausal females. Czech post-MONICA and 3PMFs studies