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Background : Matrix metalloproteinase-9 (MMP-9) is involved in the degradation of the extracellular matrix during physiological and pathological processes. Two functional polymorphisms [C –1562 T and microsatellite (CA) 13–25 ] in the promoter region of the  MMP-9  gene have been associated with several diseases. The aim of this study was to examine whether these  MMP-9  polymorphisms and haplotypes are linked with plasma MMP-9 variations in healthy subjects.

clinical chemistry and laboratory medicine

Functional polymorphisms in the promoter of the matrix metalloproteinase-9 ( MMP-9 ) gene are not linked with significant plasma MMP-9 variations in healthy subjects