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Background : One of the main issues in biobanking is the establishment of standard operating procedures for specimen collection, preparation and storage to control for pre-analytical variation. For biological fluids such as serum, there is currently a lack of sensitive biomarkers for the quality control of cryopreservation conditions.

clinical chemistry and laboratory medicine

Serum biobank certification and the establishment of quality controls for biological fluids: examples of serum biomarker stability after temperature variation