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Background : We have evaluated the performance of two newly developed automated real-time PCR assays, the COBAS Ampliprep™/COBAS TaqMan™ (CAP/CTM) and the Abbott RealTime tests, in the quantification of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) RNA. The widely used semi-automated COBAS Amplicor™ Monitor (CAM) assay served as the reference test.

clinical chemistry and laboratory medicine

Comparison of the Roche COBAS Amplicor™ Monitor, Roche COBAS Ampliprep™/COBAS Taqman™ and Abbott RealTime™ Test assays for quantification of hepatitis C virus and HIV RNA