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Background : Total tau (T-tau) and β-amyloid (1-42)  (Aβ 1-42 ) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or depressive pseudo-dementia. Differential diagnosis from dementia with Lewy bodies (DLB) in clinical settings is difficult.

clinical chemistry and laboratory medicine (cclm)

Analytical performance and clinical utility of the INNOTEST ®  PHOSPHO-TAU (181P)  assay for discrimination between Alzheimer's disease and dementia with Lewy bodies