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Background : Homocysteine metabolism is mainly governed by serum concentrations of folate and vitamin B 12 , renal function and genetic factors. It is also well documented that endocrinological disturbances influence homocysteine metabolism. However, studies on the hormones of the hypothalamic-pituitary-adrenal axis have given conflicting results.

The effects of adrenocorticotrophic hormone and cortisol on homocysteine and vitamin B concentrations