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The introduction of automation for immunoassays in recent years has brought about important and evident improvements in assay precision. Increasing standardization and comparability between platforms should enable the development of clinical guidelines and diagnostic algorithms for appropriate clinical decision making. A continuing source of variation between different automated immunoassay platforms is the sporadic effect of interfering antibodies or substances, thus causing aberrant results not supporting the patient's clinical status.

clinical chemistry and laboratory medicine

Comparative Multicentre Study of a Panel of Thyroid Tests Using Different Automated Immunoassay Platforms and Specimens at High Risk of Antibody Interference