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Urinary carcino-embryonic antigen (CEA) was measured in a follow-up study of 101 bladder carcinoma patients. Urinary CEA estimation during follow-up appears to be of clinical value. Negative results can be interpreted only in relation to previously increased values. Positive results are of value in retrospect when combined with negative data, e.g. in evaluation of suspicious bladder changes and as an early indication of renewed tumour growth. Increased CEA levels in urines from patients with urinary infection rapidly decline once the infection is cured.

clinical chemistry and laboratory medicine

Clinical Significance of Urinary Carcino-Embryonic Antigen Estimations During the Follow-Up of Patients with Bladder Carcinoma or Previous Bladder Carcinoma.  Clinical Evaluation of Carcino-Embryonic Antigen, III.