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The fasting level of free fatty acids and sugar in plasma and their response to subcutaneous epinephrine administration was studied in children suffering from congenital heart disease. In cyanotic cases elevated fasting values were found for free fatty acids (14 cases); in non-cyanotics, however, the values were normal (7 cases). In non-cyanotic heart disease the rise of free fatty acids and sugar in response to epinephrine administered subcutaneously was normal, while in cyanotic patients (10 cases) it was found to be decreased. When the studies were repeated with intravenous infusion of epinephrine the cyanotic patients showed a normal response.

Fasting Level and Epinephrine-induced Release of Free Fatty Acids in Patients with Congenital Heart Disease