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Background:  Quantification of human immunodeficiency virus type 1 (HIV-1) RNA in plasma has become the standard of care in the management of HIV-infected patients. There are several commercially available assays that have been implemented for the detection of HIV-1 RNA in plasma. Here, the new Hologic Aptima ®  HIV-1 Quant Dx assay (Aptima HIV) was compared to the Roche COBAS ®  TaqMan ®  HIV-1 Test v2.0 for use with the High Pure System (HPS/CTM).

clinical chemistry and laboratory medicine (cclm)

Comparative evaluation of the Aptima HIV-1 Quant Dx assay and COBAS TaqMan HIV-1 v2.0 assay using the Roche High Pure System for the quantification of HIV-1 RNA in plasma