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Background:  A number of studies have indicated that the conversion of clopidogrel to its active metabolite is reduced in patients who carry the CYP2C19 *2, *3, *4 or *5 loss-of-function allele, resulting in decreased response of platelet to clopidogrel treatment and worse cardiovascular outcome. The aim of this study was to develop a novel biosensor-based microarray to visually detect CYP2C19 polymorphisms.

A novel biosensor-based microarray assay for the visualized detection of CYP2C19 ∗ 2, ∗ 3, ∗ 4 and ∗ 5 polymorphisms