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Background:  In Denmark, the use of HbA 1c  in the diagnosis of diabetes was adopted from March 2012. We evaluated the change in the number of diabetes cases diagnosed by haemoglobin A 1c  (HbA 1c ) versus fasting venous plasma glucose (FPG), and estimated the influence of analytical variation and bias on the HbA 1c -based prevalence of diabetes.

Changing from glucose to HbA 1c for diabetes diagnosis: predictive values of one test and importance of analytical bias and imprecision