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Background:  Several studies have suggested that pre-B-cell colony-enhancing factor (PBEF) gene polymorphisms are associated with susceptibility to and prognosis of acute lung injury (ALI) in several populations of Caucasians. The aim of this study was to detect the distribution of  PBEF  alleles and to evaluate any potential relationship between  PBEF  polymorphisms and ALI, sepsis, and pneumonia in the Han population of Northeast China.

Association of PBEF gene polymorphisms with acute lung injury, sepsis, and pneumonia in a northeastern Chinese population