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Background:  The  ABCB1  gene encodes P-glycoprotein implicated in the development of cellular drug resistance. The aim of this study was to develop high-resolution melting (HRM) analysis for determination of  ABCB1  polymorphisms and evaluate their associations with clinical data of breast carcinoma patients.

Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis