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Left ventricular assist device (LVAD) therapy has revolutionized the way end stage heart failure is treated today. Analysis of LVAD interaction with the whole cardiovascular system and its biological feedback loops is often conducted by means of computer models. Generating real time pressure volume loops (PV-loops) in patients, not using conductance catheters but routine diagnostics to feed an in-silico model could help to predict postoperative complications.

biomedical engineering / biomedizinische technik

Parametrization of an  in-silico  circulatory simulation by clinical datasets – towards prediction of ventricular function following assist device implantation