English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Over 900 days of data records for blood pressure (systolic, diastolic) and heart rate for a single subject with mild hypertension were analyzed. From the data the Mean Arterial Pressure (MAP) was calculated. Linear regression over the entire time revealed a slight trend to higher MAP and lower heart rates. A clear circadian behaviour and a difference between work days (Mon-Fri) and weekends for the MAP data was detected. Keywords: Hypertension, Mean Arterial Pressure, Heart Rate, Weekly and Circadian Variations. Introduction Hypertension or high blood pressure is a chronic medical condition in which the blood pressure in the arteries is elevated. This requires the heart to work harder than normal to circulate blood through the blood vessels. Blood pressure is summarised by two measurements, systolic and diastolic, which depend on whether the heart muscle is contracting (systole) or relaxed between beats (diastole). Normal blood pressure at rest is within the range of 100-140 mmHg systolic (top reading) and 60-90 mmHg diastolic (bottom reading). Mild hypertension is said to be present if it is persistently at or above 140/90 mmHg. This is the case in our data. In the diagnosis of hypertension the blood pressure is measured for a few days. With the availability of 24-hour ambulatory blood pressure monitors the possible circadian changes in pressure can be detected and wrong diagnosis avoided. Still, the question remains whether the 24-hour variation of the blood pressure is caused by sleep or is based on an internal controlled process. There are controversial statements about it in reference [1, 2]. No measurements were taken during sleep. Is there a 24-hour blood pressure variation detectable in our data? There are practical no long-term data records of blood pressure and heart rate in the scientific literature. The here presented data analysis for Mean Arterial Pressure (MAP) and Heart Rate (HR) is a first tiny step to fill this gap. Furthermore, in the most published studies [2, 3] data are measured under strict controlled conditions in a hospital environment. But, what happens to people with hypertension outside the controlled conditions? The long-term impact of everyday life with work and family stress on MAP and HR should be an import topic in biomedical research and will contribute to a better understanding of hypertension.

A Case of Mild Hypertension what can we Learn from over 900 Days of Data Records?