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Over the past years, the possibility of using Subcutaneous Continuous Glucose Monitoring (CGM) devices for monitoring hospitalised patients has been explored. However, concerns about the reliability of such CGM data, particularly for subjects whose physiopathological condition compromises the correlation between interstitial fluid and blood compartment, have been raised. CGM devices based on intravascular microdialysis may represent a solution to this problem. Aim of these trials (GMD_04 and GMD_05, which involved 20 healthy and 14 T1DM subjects, respectively) was to optimise the performance of an intravascular microdialysis-based device under development at A. Menarini Diagnostics (Italy).

Optimising the glucose sampling performance of an intravascular microdialysisbased continuous glucose monitoring device for use in hospital settings