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Anabaena  sp. PCC 7120 is a filamentous cyanobacterium that serves as a model to analyze prokaryotic cell differentiation, evolutionary development of plastids, and the regulation of nitrogen fixation. The cell wall is the cellular structure in contact with the surrounding medium. To understand the dynamics of the cell wall proteome during cell differentiation, the cell wall from  Anabaena  heterocysts was enriched and analyzed. In line with the recently proposed continuity of the outer membrane along the  Anabaena  filament, most of the proteins identified in the heterocyst cell-wall fraction are also present in the cell wall of vegetative cells, even though the lipid content of both membranes is different.

The proteome of the heterocyst cell wall in Anabaena sp. PCC 7120