English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

SR-A1 is a human high-molecular-weight SR-related CTD-associated factor that links the machineries of transcription and mRNA splicing. In this study we examined the prognostic value of  SR-A1  gene expression using a semi-quantitative RT-PCR method. High  SR-A1  expression was observed in 31/81 (38.3%) breast cancer tissues and was found to be more frequent in patients with tumors of large size ( p =0.027), as well as in lymph node-positive patients ( p =0.035). Follow-up analysis revealed that low  SR-A1  expression increases the probability of both overall and disease-free survival of patients. Our results suggest that SR-A1 may possibly be characterized as a new marker of unfavorable prognosis for breast cancer.

Prognostic significance of the expression of SR-A1 , encoding a novel SR-related CTD-associated factor, in breast cancer