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FVC is a difficult maneuver for many patients, and forced expiratory volume in 6 seconds (FEV6) has been proposed as a surrogate for FVC for the diagnosis of chronic obstructive pulmonary disease (COPD). Previous studies have performed head-to-head comparisons of these thresholds but did not examine their relationships with structural lung disease, symptoms, or exacerbations.

FEV1/FEV6 to Diagnose Airflow Obstruction. Comparisons with Computed Tomography and Morbidity Indices

FEV₁/FEV₆ to Diagnose Airflow Obstruction. Comparisons with Computed Tomography and Morbidity Indices