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Temporary left ventricular assist and levosimendan for coronary artery spasm
Author(s) -
Ulrich Döpfmer,
Jan Braun,
Joachim Große,
Wolfgang Konertz
Publication year - 2005
Publication title -
interactive cardiovascular and thoracic surgery
Language(s) - English
Resource type - Journals
eISSN - 1569-9293
pISSN - 1569-9285
DOI - 10.1510/icvts.2004.103788
Subject(s) - medicine , levosimendan , milrinone , cardiology , artery , myocardial stunning , diltiazem , ventricular assist device , coronary vasospasm , cardiopulmonary bypass , anesthesia , vasospasm , intra aortic balloon pumping , bypass grafting , inotrope , heart failure , angina , ischemia , cardiogenic shock , myocardial infarction , subarachnoid hemorrhage , calcium
Coronary vasospasm is a life threatening complication in the early postoperative period after coronary artery bypass grafting. We report a 45-year-old patient with normal preoperative ventricular function who could not be stabilized using established treatments such as: systemic application of glyceryl trinitrate, diltiazem and milrinone, intraaortic balloon pumping and intracoronary injection of glyceryl trinitrate. Severe stunning of the myocardium required support with a centrifugal left ventricular assist device. Subsequent application of levosimendan, a calcium sensitizer, may have contributed to prevent recurrence of repeated episodes of coronary spasm, enabling early explantation of the assist device and a full recovery.

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