English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The chromaffin cells of the gastrointestinal mucosa were described for the first time by Heidenhain (1870) in the gastric mucosa of the rabbit and dog. Subse quently, the chromaffin cells were found in the gastrointestinal tract of various animal species and they were designated by the names of their discoverers (Heiden hain cells, Kultschitski cells, Schmidt cells, Feyrter cells). In addition, these cells were also designated as the "enterochromaffin cells" (EC). It was not until 1952 that Erspamer and Asero identified the chromaffin substance of the secretory granules of the EC cells as 5-hydroxytryptamine (5-HT), which is a specific product of these cells. The existence of other types of endocrine cells of the gastrointestinal tract was first mentioned by Kull (1913), who found the intestinal mucosa to contain non -chromaffin cells with small acidophilic granules, and by Erspamer (1939), who discovered non-argentaffin argyrophil cells in the gastrointestinal tract. Further differentiation of individual types of the endocrine cells of the gast rointestinal mucosa has become possible by the development of electron microscopic techniques (Toner 1964, Solcia et al. 1967, Orci et al. 1968). The system of endo crine cells has gradually been mapped in the gastrointestinal mucosa of the rat, cat, rabbit and man (Forssmann et al. 1969, Vassallo et al. 1969, Capella et al. 1969, Pearse et al. 1970, Vassallo et al. 1971, Nabeyama et al. 1971). In addition to serotonin, which is a well-known product of the EC cells, gastrin, secretin, cholecystokinin-pancreozymin, glucagon-like substance and enterogastrone were established as the hormonal products of different parts of the gastrointestinal mucosa (Gregory and Tracy 1964, Jorpes and Mutt 1961, Sutherland et al. 1949, Unger et al. 1966, Brown et al. 1969). The purpose of the present communication is to describe ultrastructural fea tures of endocrine cells found in the gastric and intestinal mucosa of the dog.

Endocrine Cells of the Dog Gastrointestinal Mucosa