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Literature available concerning the relationship of thyrotropin (TSH) with thyroid function and TSH responsiveness to the thyrotropin releasing factor (TRF) in the aged is limited (Snyder and Utiger 1972a, 1972b; Sakoda et al., 1972). The present study was undertaken to investigate the relationship between thyroid function and serum TSH levels in the aged, and to clarify whether the aging would show a characteristic change in the responsiveness of TSH to synthetic TRF stimulation .

Thyroid Function of the Aged as Viewed from the Pituitary-Thyroid System