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pregnancy. However, as far as we know, there are few experiments on progesterone metabolism in twins during pregnancy, and accordingly the present study was carried out on this. It was demonstrated that there is no difference between the progesterone concentrations in different sexes of fetuses or between those in single ovum twins and double ovum twins, and that in vitro conversion of labeled cholesterol to progesterone is enhanced when slices of placenta are incubated with an NADPH-generating system.

Progesterone Metabolism in Twins and Toxemias of Pregnancy Progesterone Biosynthesis in Placenta <I>in vitro</I>