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This paper uncovers the scientific foundation of traditional systems of Indian medicine: Siddha and Ayurveda, from core principles shared in modern control systems engineering. Grand challenges of modern healthcare are motivating a paradigm shift towards systems of systems (SoS) approaches. The recent emergence of modern systems biology and the concomitant growth of evidence-based research in ancient systems of holistic medicine such as Siddha and Ayurveda, practiced in India for over 5,000 years, exemplify this shift. This paper reveals a Rosetta Stone, inscribed from principles of control systems engineering, to comprehend the scientific foundations of the ancient lingua franca of Siddha and Ayurveda. This discovery provides a much-needed integrative framework, across east and west, ancient and modern, to develop a systems medicine that overcomes the reductionism of modern healthcare.

The control systems engineering foundation of traditional Indian medicine: the Rosetta Stone for Siddha and Ayurveda