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A 35-year-old man of Chinese ethnicity presented to the emergency department with fever, rash, mouth pain and visual impairment after two weeks of therapy with allopurinol. On examination, the patient had a generalized maculopapular rash, orolabial ulceration ([Figure 1][1]), keratoconjunctivitis

Prevention of severe cutaneous adverse drug reactions: the emerging value of pharmacogenetic screening