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Background: This study is performed to compare crystalloid, blood and carnitine blood cardioplegias (CP in elective coronary artery bypass grafting. Methods: Forty-five patients were randomized to threetechnique of myocardial protection (15 patients in each): Group I cold crystalloid CP, Group II tepid blood CP,Group III tepid blood CP with 5mM/L of carnitine. Blood samples taken from coronary sinus and arterial bloodwere collected in preoperative and postoperative period (6, 12, 24, and 48 postoperative hours) for enzyme measurements. Also hemodynamic parameters were measured at same time periods.Results: All the patients involved completed the study. Hemodynamic parameters in all groups were similar. Also neither preoperative nor postoperative myocardial infarction was observed in any group. CKMB and c Tn-l levels were elevated in all three groups after cross clamping until 6th hour and 12th hour for LDH all three groups. In all enzyme measurements, especially in cTn-I, decline in enzyme levels started earlier in BCCP group than other two groups. Conclusions: Although there was no significant difference between three groups in hospital mortalityand morbidity, blood with carnitine provides better myocardial protection and recovery from ischemia thando crystalloid cardioplegia and blood cardioplegia.

USAGE OF CARNITINE IN BLOOD CARDIOPLEGIA IN CORONARY ARTERY BYPASS GRAFTING