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In our previous studies we established that in normal conditions rat thrombocytopoiesis and plasma thrombocytopoietin act ivi ty depended directly on the functional state of beta-adrenergic receptors (7, 8) . The aim of the present work is to determine the extent to which non-selective beta-adrenergic actions influence thrombocyte and megakaryocyte number in thromboplastin induced acute thrombocytopenia. I t w i l l permit us to establish the role of beta-adrenergic receptors in thrombocytopoiesis regulation in extreme conditions.

CHANGES OF THROMBOCYTOPOIESIS IN RATS AFTER NON-SELECTINE BETA-ADRENERGIC TREATMENT IN CONDITIONS OF AN ACUTE THROMBOCYTOPENIA