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Results: Fifty-six patients were included in this study. The mean age of the patients was 4.2±2.3 years. The patients were examined in 3 groups according to steroid therapy. Group 1 was defined as patients who had not received steroids in the past year and who were in the remission stage, Group 2 comprised patients who had received steroids in the last year and who were in the remission stage, and Group 3 was made up of patients who were in the active nephrotic period and had received steroids. In terms of biochemical parameters (serum urea, creatinine, calcium, phosphorus, magnesium, alkaline phosphatase, parathyroid hormone, osteocalcin, vitamin D, triglycerides), there was no statistically significant difference between the 3 groups. Group 3 had a higher ratio of calcium/creatinine and protein/ creatinine in spot urine than Groups 1 and 2. Of 56 patients, 40 patients had eye examinations. There was no statistically significant difference determined in terms of side effects of steroid treatment.

The Effects of Steroid Therapy on Bone and Eyes in Children with Nephrotic Syndrome