English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

61 Sahin, Thyroid dysfunction in the geriatric population / doi: 10.14744/ijmb.2019.54254 hypothyroidism is the most common thyroid function disorder in geriatric patients [2, 3]. Hyperthyroidism is observed at a rate of 0.5% to 6% in geriatric patients and affects mainly the cardiovascular system (atrial fibrillation, congestive heart failure) and bones (increased bone cycle, osteopenia) [4]. The incidence of goiter, an enlarged thyroid gland, has been reported to reach 70% in the aging population in regions with iodine deficiency [5]. Yet the diagnosis and treatment of thyroid diseases, particularly in geriatric patients, can be difficult. The symptoms and values may not be the same as those typically seen in young adults. This may be further complicated by comorbidities, which often leads to delayed diagnosis and more serious disease progression, making treatment more difficult. It has been recommended that all individuals in the geriatric age group be screened for thyroid dysfunction since these symptoms and findings may remain hidden [6]. The aim of the present study was to identify and analyze the incidence of thyroid dysfunction in patients over 65 years of age in Corum province, Turkey. Materials and Methods The demographic and laboratory results of patients aged over 65 years living in Corum province, Turkey, who presented at Hitit University Corum Erol Olcok Education and Research Hospital for any reason were used in the study. Permission was granted for the study by the Hitit University Non-Interventional Research Ethics Committee, dated and numbered 29/01/201943. The results of thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) tests as well as demographic characteristics of 220 randomized patients were retrospectively investigated. Patients with total or partial thyroidectomy surgery and those receiving any medical thyroid treatment were excluded from the study. Thyroid function tests (TFT) were measured using the electrochemiluminescence method on a Siemens Advia Centaur XP model immunoassay autoanalyzer (Siemens Healthineers, Erlangen, Germany). The normal intervals for TFT at this center are TSH 0.35–5.50 μIU/mL, FT4 0.89–1.76 ng/dL, and FT3 2.30–4.20 pg/mL. Hypothyroidism was defined as FT4 <0.89 ng/dL and TSH >5.50 μIU/mL, with subclinical hypothyroidism defined as normal free hormone levels and a TSH >5.50 μIU/mL. Hyperthyroidism was defined as FT4 >1.76 ng/dL and TSH <0.35 μIU/mL, while subclinical hyperthyroidism was defined as normal free hormone levels and TSH <0.35 μIU/mL. Patients were divided into 5 groups: subclinical hypothyroidism, hypothyroidism, euthyroid, subclinical hyperthyroidism, and hyperthyroidism. Statistical analysis All of the statistical analyses were performed using the IBM SPSS Statistics for Windows, Version 22.0 (IBM Corp.; Armonk, NY, USA). Demographic and biochemical features were presented as continuous or categorical variables, as appropriate. The Kolmogorov-Smirnov test was used to assess normality. Variables were presented as median (25th-75th percentile, interquartile range [IQR]) since they were not normally distributed. Comparisons between groups were performed using the Mann-Whitney U test. A chi-square test was used to evaluate the differences between categorical variables. All reported p values were 2-tailed, and values less than 0.05 were considered statistically significant.

Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province