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DOI:10.14744/bej.2018.41736 Beyoglu Eye J 2018;3(2): 52-57 Original Article Guclu et al., Ferritin level in ischemic optic 53 ropathy in multiple studies (7-9). Serum ferritin is an inflammatory marker, which has been reported to be related to the pathogenesis of some diseases, such as diabetes, cancer, heart diseases, neurodegenerative diseases, and age-related macular degeneration (10, 11). Iron plays an important role in cell functions, such as oxygen transport, cell division, mitochondrial adenosine triphosphate formation, and myelin production (12, 13). Multifocal visual evoked potential, ultrasonography, diffusion-weighted magnetic resonance imaging, visual field tests, fluorescein angiography, optical coherence tomography, and laser speckle flowgraphy have been reported to be helpful in distinguishing ON from NAION in multiple studies. (1, 3, 14-20). The aim of this study was to demonstrate and compare the levels of Vit B12, folic acid, serum ferritin, serum iron, and total iron binding capacity (TIBC) in patients with ON and NAION. The objective was to determine whether these simple and inexpensive laboratory methods could be used to differentiate between ON and NAION.

Distinguishing non arteritic ischemic optic neuropathy and optic neuritis with serum Vitamin B12, ferritin and folic acid levels.