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dicated that increased CIMT is a strong predictor of future cardiovascular events (2). CIMT is a noninvasive method performed using ultrasound imaging to measure the artery wall thickness (3). CIMT is a marker of subclinical atherosclerosis (asymptomatic organ damage) and should be evaluated in all asymptomatic adults or patients with a moderate risk of cardiovascular disease. Intima-media thickness values >0.9 mm should be considered abnormal (4, 5). Linear mixed model (LMM) is generally recommended because of its potential to provide more suitable data in terms of temporal changes (6, 7). We agree with you about using LMM instead of the Friedman test because LMM can provide more information for our study.

the anatolian journal of cardiology

Response to: Percutaneous closure of a secundum atrial septal defect through femoral approach in an adult patient with interrupted inferior vena cava and azygos continuation