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Materials and methods. Immunohistochemical study of invasive рТ1-4N0Mx endometrioid endometrial carcinoma (EEC) (n=56; age – 42–83 years), invasive рТ1-4N1-2Mx EEC (n=30; age – 48–79 years), samples of normal proliferative endometrium (PE) (n=30; age – 41–62 years) was performed. Molecular-genetic study of invasive рТ1-4N0Mx EEC (n=10; age – 45–67 years), invasive рТ1-4N1-2Mx EEC (n=10; age – 44–63 years), samples of PE (n=10; age – 46–59 years) was performed.

patologìâ

Comparative characteristics of the transcriptional activity of CDH1, CTNNB1, VEGFA genes and expression of proteins E-cadherin, β-catenin and VEGFA, coded by these genes in metastatic and non-metastatic endometrioid endometrial carcinoma