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Materials and methods. 139 children with the average age of 13.6 were examined; all of them had an infiltrative pulmonary tuberculosis and received long-term treatment with rifampicin at the Zaporizhzhia Regional Tuberculosis Dispensary. Also, 32 medical workers were examined and divided into high and low risk groups of C. difficile infection depending on the closeness of their contacts with children at the department. To detect C. difficile toxins A/B in the stool an ELI method was applied using the ELISA test system (Diagnostic Automation, Inc., Calabasas, USA). The amount of toxins ranged from 1 ng and more in 1 ml of feces sample was considered as diagnostic.

Detection of Clostridium difficile toxins A/B in the stool specimens from patients and medical staff of the children's antituberculosis department