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The modern standards and algorithms of antimicrobial therapy, that ensure a high level of the treatment’s quality and prevention of the most infectious-inflammatory diseases, provide wide using of chemotherapeutic agents. However, the modern medicines do not always have satisfactory chemotherapeutic and pharmacological properties; this fact is most often associated with the resistance of microorganisms to them. That is why the creation of the new chemotherapeutic drugs by natural antibiotics’ chemical and microbiological modification, the chemical synthesis of the new substances among the various classes of organic compounds is a topical problem.

Trіazolo[1,5-c]quіnazolіnes Synthesis, antimicrobial and antifungal activity [quinazolin-4(3H)-ylidene]hydrazides of carboxylic acids (Message 1)