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Gigantomastia is characterized by excessive mammary tissue growth [1]. Patients with gigantomastia experience physical and psychological discomfort, such as pain, skin ulceration, loss of nipple sensation, and social stigma. It mainly occurs during puberty or pregnancy. Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign proliferation of nonspecialized fibrous mammary stroma [2]. It is usually asymptomatic and found incidentally on breast biopsies of premenopausal women. Although rare, PASH sometimes develops into unilateral breast nodules or masses [2,3]. However, bilateral diffuse PASH that causes rapid breast enlargement without forming discrete nodular masses is extremely rare, and has hardly been reported in the literature. The etiology of PASH has not been well established. It is known to express progesterone and estrogen receptors, indicating that it is hormone-sensitive [3]. Pathologically, it is characterized by anastomosing slit-like pseudovascular spaces lined by bland spindle-shaped cells [4,5]. Gigantomastia due to PASH is very rare. Fewer than 10 cases have been reported in the literature, and no recurrent cases have previously been described. In this article, we report a case of recurrent gigantomastia in a patient who had received primary reduction mammoplasty at another hospital, resulting in D-cup breasts. Recurrence occurred as rapidly progressing breast enlargement. In Jun Hyeok Kim, Seung Eun Baek, Tae Kyung Yoo, Ahwon Lee, Deuk Young Oh

Relapsed Bilateral Gigantomastia Caused by Pseudoangiomatous Stromal Hyperplasia after Reduction Mammoplasty