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Breast cancer is the second most common cancer in Korean women, representing 14.8% of all newly diagnosed cancers, and this proportion is gradually increasing [1]. Many flap methods are being introduced for the reconstruction of breast parenchymal defects after breast cancer surgery. Among them, myocutaneous flaps using the latissimus dorsi (LD) muscle are widely used because of their high vascularity and flexibility that facilitate shape control in breast reconstructive surgery. A drawback of the LD flap is the risk of donor-site morbidity on the back. The most common complication is seroma formation, and the incidence of seroma as a complication has been reported to vary, ranging from 1% to 56% [2,3]. Despite such a high incidence, only limited research on donor-site seroma formation has been conducted [4,5]. Several mechanisms of seroma formation have been reported. The donor site of an LD myocutaneous flap may have hidden bleeding, and prolonged lymphatic leakage may cause fluid collection. Further, the shearing force generated by the constant movement of a patient can cause a disruption between the skin and the underlyDa Woon Lee, Sang Gue Kang, Min Sung Tak

Will a Fibrin Sealant be Effective as a Seroma Reductant and a Hemostatic Agent in Breast Reconstruction Using a Latissimus Dorsi Flap?