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In two splenectomized siblings with congenital dyserythropoietic anemia type-II (CDA-II) and iron overload excess of Pappenheimer bodies reaching 46.4% and 15.9% respectively was found. Cause, significance and differential diagnosis of this finding were discussed.

acta medica

Excess of Pappenheimer Bodies (Siderocytes) in Two Splenectomized Siblings with Congenital Dyserythropoietic Anemia – Type II (CDA-II) and Iron Overload